Skeletal muscle protein synthesis in adult and old rats
نویسندگان
چکیده
منابع مشابه
Effect of glucocorticoid excess on skeletal muscle and heart protein synthesis in adult and old rats.
This study was carried out to analyse glucocorticoid-induced muscle wasting and subsequent recovery in adult (6-8 months) and old (18-24 months) rats because the increased incidence of various disease states results in hypersecretion of glucocorticoids in ageing. Adult and old rats received dexamethasone in their drinking water for 5 or 6 d and were then allowed to recover for 3 or 7 d. As dexa...
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Age-associated low-grade systemic inflammation may contribute to sarcopenia. We hypothesized that skeletal muscle mass and protein synthesis rate would be reduced in old rats exhibiting persistent low-grade inflammation compared to age-matched controls. Male 24-month-old Wistar rats exhibiting a low-grade systemic inflammation for at least one month (LGI group) were compared to non-inflamed rat...
متن کاملSkeletal muscle regeneration in very old rats.
This study was undertaken to assess the regenerative capacity of skeletal muscle in rats near the end of their normal life span. Two experiments were performed. In the first, extensor digitorum longus (EDL) muscles were cross-age transplanted from 32-month-old male inbred Wistar (WI/HicksCar) rats in place of an EDL muscle in 4-month-old hosts. The other EDL muscle in the hosts was autotranspla...
متن کاملMyogenic regulatory factors during regeneration of skeletal muscle in young, adult, and old rats.
Myogenic factor mRNA expression was examined during muscle regeneration after bupivacaine injection in Fischer 344/Brown Norway F1 rats aged 3, 18, and 31 mo of age (young, adult, and old, respectively). Mass of the tibialis anterior muscle in the young rats had recovered to control values by 21 days postbupivacaine injection but in adult and old rats remained 40% less than that of contralatera...
متن کاملLeucine content of dietary proteins is a determinant of postprandial skeletal muscle protein synthesis in adult rats
BACKGROUND Leucine (Leu) regulates muscle protein synthesis (MPS) producing dose-dependent plasma Leu and MPS responses from free amino acid solutions. This study examined the role of Leu content from dietary proteins in regulation of MPS after complete meals. METHODS Experiment 1 examined 4 protein sources (wheat, soy, egg, and whey) with different Leu concentrations (6.8, 8.0, 8.8, and 10.9...
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ژورنال
عنوان ژورنال: Reproduction Nutrition Development
سال: 1999
ISSN: 0926-5287
DOI: 10.1051/rnd:19990134